Desirial 19mg/ml 2-1ml prefilled syringes


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DESIRIAL® is the first gel based on antioxidant hyaluronic acid specially formulated to preserve the intimate health of women .

Entirely dedicated to women’s intimate health, the DESIRIAL® viscosupplementation solution developed by Laboratoires Vivacy opens up new treatment options in gynecology and intimate plastic surgery.

Up to 80% of women who enter menopause are affected by vaginal dryness and approximately 50% of postmenopausal women continue to experience vaginal dryness.

Vaginal and/or vulvar dryness can affect women throughout their lives, whether iatrogenic (eg isotretinoin, tricyclic antidepressants, neuroleptics, etc.), or related to menopause, in particular in the absence of hormone replacement therapy (HRT).

During menopause, a decrease in estrogen secretion is observed, which has an effect on the fibroblasts, and leads to a progressive hypotrophy of the dermis with the flattening of the dermo-epidermal junction:

– The vaginal mucosa becomes dry (the connective tissue has less vascularization, is less hydrated and becomes thinner), just like the skin as a whole. Less nourished glandular cells become trophic and begin to malfunction.
– The skin loses its elasticity. Collagen and elastin fibers degenerate and shrink, fibroblasts become hypoactive and type III collagen increases at the expense of type I collagen.

As a result, skin dryness, loss of elasticity, and fragility appear. Falling estrogen levels (related to menopause) leads to labia majora hypotrophy, also characterized by dryness of the vulva.

The injection of DESIRIAL® cross-linked hyaluronic acid into the dermis of the lip can help rehydrate, biostimulate and restore the activity of fibroblasts and maintain the proper functioning of female genital tissue

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